2023.08-至 今，中国科学院宁波材料技术与工程研究所，副研究员
2020.11-2023.08，中国科学院宁波材料技术与工程研究所，客聘助理研究员
2020.12-2023.04，南京农业大学，博士后
2017.09-2020.09，中国科学院宁波材料技术与工程研究所，获材料物理与化学博士学位
2016.04-2017.08，中国科学院宁波材料技术与工程研究所，科研助理
2014.09-2015.11，英国伦敦国王学院，获分子生物医学硕士学位
2010.09-2014.06，南京农业大学，获生物工程学士学位
徐梦佳，博士，中国科学院宁波材料技术与工程研究所副研究员，硕士生导师，宁波市领军与拔尖人才培养计划第三层次，慈溪市上林人才培养工程第三层次。2020年毕业于中国科学院大学，获得工学博士学位后，2021-2023年在南京农业大学进行博士后研究，出站后留宁波材料所担任客聘助理研究员，同年晋升副研究员。主要从事植物/海洋生物活性物质功效评价及肠道菌群互作改善慢性肝病机制探究；疾病标志物体外检测探针与传感策略构建。近年来以第一作者/通讯作者于Sens. Actuators B Chem., Mater. Today Bio, Talanta, Food Frontiers, Foods, Front. Med等期刊发表论文10篇，共发表SCI收录论文21篇，申请发明专利9项，获授权5项。作为项目负责人主持国家自然科学基金项目、宁波市公益计划项目（重点），宁波市自然科学基金项目（已结题）、中央高校基本科研专项项目（已结题）、医院横向技术服务等项目；作为核心成员参与宁波市自然科学基金项目（重点项目）、慈溪市人民医院医疗健康集团（慈溪市人民医院）重点学科建设（感染科）项目、宁波市生命健康重大项目（已结题）和宁波市公益项目（已结题）等项目，参加10余次国际/国内会议。
研究方向：
天然生物活性物质筛选及纳米递送体系构建；
基于核酸纳米探针的传感技术开发
联系方式：xumengjia@nimte.ac.cn
发表论文：
(1) Fuqiang Song, Anqi Ye, Linyuan Jiang, Yang Lu, Yanzhen Feng, Rong Huang, Siting Du, Xiaoyu Dong, Ting Huang, Ping Li, Liangliang Yang, Jinjing Zhang**, Mengjia Xu***, Li Cheng****, Jian Xiao*. Photothermal-enhanced silver nanocluster bioactive glass hydrogels for synergistic antimicrobial and promote wound healing. Materials Today Bio, 2024, 30, 101439.
(2) Xu M.#, Feng H.#, Guo M*. Potential hypoglycemic and hypolipidemic bioactive constituents in Cyclocarya paliurus leaves explored by affinity ultrafiltration with α-glucosidase and pancreatic lipase. eFood, 2023, 5, e123. http://doi.org/10.1002/efd2.123.
(3) Xu M., Wang X., Tian J., Chen, J*., Wei X*., Li W*. A clamp-improved universal amplified system for ratiometric fluorescent detection of single-nucleotide polymorphisms coupled with a novel dual-emissive silver nanocluster. Sensors and Actuators B: Chemistry. 2022, 367: 132151. （中科院一区TOP期刊，IF=8.4)
(4) Xu M., Li Z., Zhao X., Li W*. Prebiotic properties of exopolysaccharides from Lactobacillus helveticus LZ-R-5 and L. pentosus LZ-R-17 evaluated by in vitro simulated digestion and fermentation. Foods. 2022, 11: 2501. (中科院二区，IF=5.2)
(5) Xu M., Xing S., Zhao Y., Zhao C*. Peptide nucleic acid-assisted colorimetric detection of single-nucleotide polymorphisms based on the intrinsic peroxidase-like activity of he min-carbon nanotube nanocomposites. Talanta. 2021, 232: 122420. （中科院一区TOP期刊，IF=6.1)
(6) Hua X.#, Xu M.#, Yang M.#, Zhang Y., Ma J., Cheng L., Chu C., Wu Z., Guo M.* Hypoglycemic and hypolipidemic bioactive compounds from edible traditional Chinese medicines and their action of mechanisms explored by multitarget affinity ultrafiltration with liquid chromatography–mass spectrometry. Food Frontiers. 2024, 1–20. （中科院二区，IF=7.4)
(7) Chen C.#, Xu M.#, Zheng Q., Li D., Cheng L., Sun J., Wu Z.* Biological evaluation of carbazoyl hydrazine derivatives as potential Pim-1 kinase inhibitors for the treatment of human liver cancer. Journal of Molecular Structure. 2024, 1295: 136742. （中科院二区，IF=3.8)
(8) Cao J., Xu Z., Xu M.*, Ma Y.*, Zhao Y. A two-stage framework for optical coherence tomography angiography image quality improvement. Frontiers in Medcine, 2022, 10: 1061357. （中科院三区，IF=3.9)
(9) Xu M., Fu P., Xing S., Zhao Y., Zhao C*. A PNA-DNA2 triple-helix molecular switch-based colorimetric sensor for sensitive and specific detection of microRNAs from cancer cells. ChemBioChem. 2020, 21: 2667-2675. （中科院三区，IF=3.2)
(10) Xu M., Xing S., Xu X., Fu P., Xu W., Zhao C*. Label-free colorimetric aptasensor for highly sensitive and selective detection of proteins by using PNA/DNA hybrids and a cyanine dye. Analytical Methods. 2018, 10: 3824-3829. （中科院三区，IF=3.1)
(11) Yang Zhao, Li Cheng, Mengjia Xu, Chao Zhao*. Ultra-sensitive detection of microRNAs using an electrochemical biosensor based on a PNA-DNA2 three-way junction nanostructure and dual cascade isothermal amplification. Analytica Chimica Acta, 2025, 1345, 343755.
(11) Wei H., Yu S., Zhang Y., Zhang H., Ma Y., Xu M., An P., Zhou Y., Halila S.*, Wei Y.*, Chen J*. Injectable chitosan/xyloglucan composite hydrogel with mechanical adaptivity and endogenous bioactivity for skin repair. Carbohydrate Polymers, 2023, 313, 120904. （中科院一区TOP期刊，IF=11.2)
(12) Wang X., Tian J., Tang N., Zhang X., Xiao L., Xu M., Dong M., Li W*. In vitro simulated digestion and fecal fermentation of exopolysaccharides from Lacticaseibacillus paracasei GL1. Food & Function, 2023, 14, 5120.
(13) Yu X., Ding S., Zhao Y., Xu M., Wu Z., Zhao C*. A highly sensitive and robust electrochemical biosensor for microRNA detection based on PNA-DNA hetero-three-way junction formation and target-recycling catalytic hairpin assembly amplification. Talanta. 2023, 266: 125020.
(14) Wang X., Xu M., Xu D., Ma K., Zhang C., Wang G., Dong M., Li W*. Structural and prebiotic activity analysis of the polysaccharide produced by Lactobacillus helveticus SNA12. Carbohydrate Polymers, 2022, 296: 119971.
(15) Guo S., Chang H., Xu M., Wang C., Wei H., Li D., Chen J*., Zhou Y*., Liu Y*. Co2+-mediated hydrogels with enhanced mechanical properties for flexible sensing. ACS Applied Polymer Materials. 2022, 4(9): 6403-6413.
(16) Fu P., Xu M., Xing S., Zhao Y., Zhao C*. Dual cascade isothermal amplification reaction based glucometer sensors for point-of-care diagnostics of cancer-related microRNAs. Analyst. 2021, 146: 3242-3250.
(17) Wang X., Li W., Xu M., Tian J., Li W*. The microbial diversity and biofilm-forming characteristic of two traditional Tibetan Kefir grains. Foods. 2021, 11(1): 12.
(18) Fu P., Xing S., Xu M., Zhao Y., Zhao C*. Peptide nucleic acid-based electrochemical biosensor for simultaneous detection of multiple microRNAs from cancer cells with catalytic hairpin assembly amplification. Sensors and Actuator B: Chemistry. 2020, 305: 127545.
(19) Gao T., Xing S., Xu M., Fu P., Yao J., Zhang X., Zhao Y., Zhao C*. A peptide nucleic acid–regulated fluorescence resonance energy transfer DNA assay based on the use of carbon dots and gold nanoparticles. Microchimica Acta. 2020, 187: 375.
(20) Xu X., Xing S., Xu M., Fu P., Gao T., Zhang X., Zhao Y., Zhao C*. Highly sensitive and specific screening of EGFR mutation using a PNA microarray-based fluorometric assay based on rolling circle amplification and graphene oxide. RSC Advances. 2019, 9: 38298-38308.
(21) Xing S., Xu X., Fu P., Xu M., Gao T., Zhang X., Zhao C*. Colorimetric detection of single base-pair mismatches based on the interactions of PNA and PNA/DNA complexes with unmodified gold nanoparticles. Colloids and Surfaces B: Biointerfaces. 2019, 181: 333-340.
(22) Xu W., Xing S., Xu X., Xu M., Fu P., Gao T., Zhao C*. Peptide nucleic acid-assisted label-free detection of single-nucleotide polymorphisms based on light scattering of carbon nanotubes. ACS OMEGA. 2018, 3: 17835-17841.
(23) Yip Y., Pernigo S., Sangera A., Xu, M., Parsons M., Steiner RA*., Dodding MP*. The light chains of kinesin-1 are autoinhibited. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2016, 113(9): 2418-2423.
授权专利：
- 徐梦佳; 魏晓捷; 一种比率型银纳米簇荧光探针及其制备方法与应用, 2023-4-7, 中国, ZL 202210153135.6
- 徐梦佳; 赵超; 邢淑; 付盼; 徐小军; 徐皖星; 一种凝血酶检测方法及其试剂盒, 2021-6-8, 中国, ZL 201810552184 .0
- 徐梦佳; 赵超; 徐皖星; 邢淑; 一种检测单核苷酸多态性的方法, 2019-6-25, 中国, 201910553022 .3
- 徐小军; 赵超; 邢淑; 付盼; 徐梦佳; 徐皖星; 基因缺失突变的荧光检测试剂盒和荧光检测方法, 2021-10-8, 中国, ZL 201810682300.0
- 付盼; 赵超; 徐皖星; 邢淑; 徐梦佳; 一种巯基功能化肽核酸增强银纳米簇荧光信号检测单核酸多态性的方法及其应用, 2023-6-6, 中国, 201910608658 .3
申请专利：
(1) 徐梦佳；周梦琦；李伟；郭明全；一种结合瑞士乳杆菌的适配体及其筛选方法，2024-12-27，中国，202411945866.X
(2) 郭明全；徐梦佳；一种胰脂肪酶固定化复合纳米磁珠、制备方法及应用。
(3) 魏晓捷;肖健;宋富强;徐梦佳;张宏宇;郭明全;成立;孙峰;邬芬赞;叶安琪; 一种可注射温敏型水凝胶伤口敷料及其制备方法和应用, 2024-9-6, 中国, 202411248827.4
(4) 成立;肖健;蒋林原;徐梦佳;张宏宇;郭明全;魏晓捷;孙峰;邬芬赞;一种创面愈合材料及其制备方法，2024-7-31, 中国, 202411036956.7
(5) 吴梓苗；郭明全；徐梦佳；一种提高酶固定化效率从天然提取物中筛选活性物质的方法，2024-12-24，中国，202411907687.7
(6) 郭明全; 徐梦佳. 青钱柳中多靶标活性配体的筛选及其应用. 申请号：CN202311495706.5，申请时间：2024.03.05
(7) 付盼; 赵超; 徐梦佳; 邢淑; 张晓康; 一种microRNAs检测试剂盒及检测方法和应用, 2020-7-17, 中国, 202010691475 .5
(8) 邢淑; 赵超; 徐皖星; 徐梦佳; 徐小军; 付盼; 一种单核苷酸多态性的比色检测方法及试剂盒, 2018 -5-31, 中国, 201810552198 .2